This protocol does not adhere to the design that ITMN CEO Dan Welch spoke of on a recent webcast (#msg-33497987).
Welch had said that Roche would test the two drugs in varying dose ratios. However, all of the cohorts in the actual trial use a 10:3 ratio of total daily R7128 to total daily ITMN-191.
Nice find thanks! I don't see what is being done in cohort C (vs b & d).
to be off topic a little I saw a poster about Naglazyme A Follow-Up of Enzyme Replacement Therapy in Two MPS VI Patients with Poorly Engrafted Bone Marrow Transplantation. I thought BMT was not an option for MPS VI. A little more research and I found it is an option in some do you know how common? Am I right in thinking BMT is not an option in Morquio too. TIA!