Replies to post #68405 on Biotech Values

[iwfal]

3. After two weeks on ITMN-191 + R7128, patients will continue with 46 weeks of SoC (a total treatment duration of 48 weeks).

That is a pity - it would be nice to understand relapse rate.

[DewDiligence]

More ITMN tidbits from the DB webcast:

Dan Welch thinks Pirfenidone has a much bigger upside for ITMN than ITMN-191 does; however, he will reconsider such a ranking if it turns out that an all-oral HCV cocktail including ITMN-191 works as well as—or better than—interferon-based regimens.

[genisi]

>The exact dosing protocol in the trial is being kept a secret (at Roche’s behest)<

Not a secret anymore. Interesting protocol:

http://clinicaltrials.gov/ct2/show/NCT00801255?term=Roche+hcv&rank=9

The higher dose will only be tested if supported by safety data from the first 2 low dose cohorts and ITMN-191 dosed q8h.