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ocyanblue

04/11/08 4:09 PM

#5637 RE: steveporsche #5632

Obtaining financing certainly those not seem to be a problem for them.

If DNDN can raise as much money as they need, why should they worry about keeping investors' interest between the interim and the final and risk IMPACT failure?

It seems clear that optimizing the power of the interim was a large, if not the major, reason behind the complex maneuver to change to OBF as the alpha spending function, raise the interim trigger and lower the final trigger. The computation to set these numbers properly is sufficiently complex that this would not be done without serious data analysis.

The open question still is what new data have they gotten that drove them into trying to solve that problem instead of just sitting tight waiting for the 360 trigger which was powered at more than 90% based on just the old D9901+D9902a data?