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Replies to #61295 on Biotech Values
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DewDiligence

04/10/08 8:36 PM

#61296 RE: zipjet #61295

>"These observations may be due to the emergence of neutralizing antibodies (NAbs) in patients taking IFN-beta."
There may also be antibodies to Copaxone but I am not aware of a test for it.<


In general, smaller is better when it comes to immunogenicity, and the constituent peptides in Copaxone are very much smaller than ifn-beta (5-11 kD vs 23 kD).

p.s. Glad to hear that your wife is doing OK.
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genisi

04/16/08 4:04 AM

#61446 RE: zipjet #61295

Tysabri and JC virus activation - The poster at the 60th annual AAN say that virus was detected in the CSF of one patient at four months.