>"These observations may be due to the emergence of neutralizing antibodies (NAbs) in patients taking IFN-beta." There may also be antibodies to Copaxone but I am not aware of a test for it.<
In general, smaller is better when it comes to immunogenicity, and the constituent peptides in Copaxone are very much smaller than ifn-beta (5-11 kD vs 23 kD).
p.s. Glad to hear that your wife is doing OK.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”