Evithrom is DOA. Surgical time plays a huge role in deciding what products to use in surgery. The thrombin products are used once the procedure is essentially complete & the surgeon is just drying the field before closing. No surgeon is going to wait 30 minutes and the surgeon doesn't know if their going to need the product for hemostatis or the quantity so you'd be wasting resources by ordering it ahead of time.
If ZGEN could get Baxter to switch to rthrombin then they would be huge, but I don't know whether a clinical trial would have to be conducted.
I would like to get an answer from ZGEN's management or BSR why Baxter is not switching to rthrombin if the immunogenicity concerns are so important.
Rock: Surgeons are the most impatient people in all the land. I think they select residents based on that trait. LOL.
One point however, if the OR staff know in advance what cases will need or likely need thrombin they can thaw it in advance of the case beginning and have it handy for the surgeon. My issue is when I need control of hemorrhage I need it immediately. I just can't wait that long for thawing.
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