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Replies to #1411 on Biotech Values
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swampboots

03/08/04 8:14 PM

#1415 RE: DewDiligence #1411

DEW- RE:"...... announced a two-year extension of a collaborative agreement on the joint discovery and development of novel genes and proteins as pharmaceutical targets and therapeutics, including further research related to interleukin-9 (IL-9)."
Is it the "........including research related to interleukin-9 (IL-9)". that may be a stealth substitute for uh a former, but is worded as a beeezy business as usual extention, that sets off those alarms?

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winchem21

03/08/04 9:18 PM

#1416 RE: DewDiligence #1411

Today's news seems to be a positive long-term development. I am glad to see GENR's continued partnership with Ludwig, since they have so much technical expertise in this area.

Ludwig also recently (Nov 11, 2003) was awarded a patent for IL-9 conjugates (6,645,486).

"The methods of this invention relate to immunizing animals with conjugates of cytokines and a carrier to induce a prolonged high titre antibody response specific for the cytokine."

It seems that GENR has been trying to obtain/license IP outside of the MEDI agreement for some time; my guess because of the greater long-term profit potential and interest.

There are also questions in the literature--that have not been answered in subsequent articles--on the effectiveness of treating asthma by targeting only IL-9. Success will likely require going after multiple targets simultaneously. It seems that Ludwig may be well suited for this.

wc21