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Re: DewDiligence post# 1411

Monday, 03/08/2004 9:18:09 PM

Monday, March 08, 2004 9:18:09 PM

Post# of 257295
Today's news seems to be a positive long-term development. I am glad to see GENR's continued partnership with Ludwig, since they have so much technical expertise in this area.

Ludwig also recently (Nov 11, 2003) was awarded a patent for IL-9 conjugates (6,645,486).

"The methods of this invention relate to immunizing animals with conjugates of cytokines and a carrier to induce a prolonged high titre antibody response specific for the cytokine."

It seems that GENR has been trying to obtain/license IP outside of the MEDI agreement for some time; my guess because of the greater long-term profit potential and interest.

There are also questions in the literature--that have not been answered in subsequent articles--on the effectiveness of treating asthma by targeting only IL-9. Success will likely require going after multiple targets simultaneously. It seems that Ludwig may be well suited for this.

wc21

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