Replies to post #4292 on GTC Biotherapeutics (fka GTCB)

[Pre_Clinical]

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>So the question is, how common is this, and to what degree does the mammary gland glycosylation pathway differ from other expression systems, in particular CHO cells?<

That's a pretty poorly designed experiment if you're trying to figure out if the PK/PD of goat-derived material is the same as the stuff currently used in the clinic.
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Thanks for your input. I'm trying to evaluate the promise of this company's technology platform as a potential investment. Do you know if an any data exists which compares the PK/PD profiles of a set of goat derived recombinant proteins vs. the same set of proteins expressed in CHO cells? Thanks in advance. -PC