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nerdseeksblonde

06/02/07 12:07 PM

#4006 RE: nerdseeksblonde #4004

you really need to look at pix here:

Imagine if they could get data like this
as a function of time and correlate
with survival ( raw and improved):
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=17341312

They would have the only in house immunomodel with
any predictive value after just a few patients
died. Insted, they have a cartoon and a hard
to read graph and confusing PR on the cd54
FACS and an MOA that doesn't make sense.

They probably wouldn't even need to separate
the cells as the principal component analysis would
probably tell them what they have. Rather than try
to guess what is important with FACS, you
can get just about everything here ( Again,
as a function of time).

Sure, this doesn't work for small molecules and is
not accurate due to protein translation rate differences, but
measuring the bleach or a selected cytokine based on
gene results is not difficult once you have
some idea what is important.