Replies to post #44965 on Biotech Values

[palindromy]

Dew, you might even be right on the specific issue here. But I would hardly dimiss so easily the views of the one person who has been right about DNDN.

I doubt very much if approable would put David in a bad position. Anybody who actually followed his advice would have a fantastic return today. Anybody who follows his advice for May 15th will have a completely hedged position.

Calling ideas garbage and attacking each other personally I thought were the hallmark of other message boards.

[AlpineBV_Miller]

I think it would be more truthful for you to say that a CU program puts you in an impossible situation.

Geez, Dew, I thought we were past this kind of personal attack stuff on this board.

Let's say for a moment your assertion that DNDN can afford to do a CU program is correct. Ignoring the impact on 9902b for a moment, I would welcome such a program because it would clearly demosntrate the high level of demand for Provenge. Retailers long ago leaned the power of providing samples to test out the market and refine their marketing pitch. A CU program would be exactly that for Dendreon -- one big test marketing exercise.

If we return to reality, it's still a garbage idea because the CU program would rob patients from the 9902b trial. CU programs are limited by resources and the FDA as to how many men can be treated. Delays in completing enrollment would delay when this drug can make it into ALL patients' hands and I don't think that's particularly ethical.

[iwfal]

Impossible in what way? Your argument that a CU program would preclude full 9902b enrollment doesn’t hold water because 9902b is almost fully enrolled right now.

I would suggest this is a odd statement. Clearly it is virtually impossible to run a trial if the drug is freely available to that population. Not fully enrolled is not fully enrolled. Why would anyone take a chance of getting placebo when they could be sure of getting the treatment via CU? Experimenting on humans is hard.

[iwfal]

I think it would be more truthful for you to say that a CU program puts you in an impossible situation.

Dew - an interesting question:

Why is it you assume that people with whom you interact often behave in ways counter to reality (due to personal motivations) but that FDA bureaucrats and AC members do not have the same flaw?

Just because you do not know them well enough to understand their personal motivations you assume they have none?

Not attacking. Just finding it odd that you can always think all of us biased, but not anyone in the fda.

Clark