Replies to post #3264 on GTC Biotherapeutics (fka GTCB)

[floblu14]

Thank you DB9 & Dew - still waiting for a Merrimack press release although the trial data is quite impressive & has the FDA blessings

It appears I was NOT hallucinating - LOL

[mblimon]

New Phase-2 RA trials of MM-093 .

I am a bit surprised about the increments in dosing. It started with 2.5, 7.5 and 20mg and is now at once increased to 60mg. That is 3 times the highest dose during the previous trials and 24 times the lowest dose of those trials. Was so little known about safety limits before? Otherwise they wouldn't have been so conservative in their previous dosing, I guess?

[ThomasS]

This implies that we may not see "robust" efficacy data until after we get interim or full results from the 60mg dosing. Of course, I'm happy about safety, but we need the obvious efficacy.