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Replies to #43602 on Biotech Values
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iwfal

03/26/07 4:10 PM

#43604 RE: upndown1313 #43602

I do point out that there were some improvements in plaque reduction in the secondary endpoints in ILLUMINATE

I would suggest that this should worry a CETP inhibitor fan - that it causes more deaths while having some positive effect on atheroma volume. It means that inhibition of CETP is making the remaining atheroma more rupture prone.

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AlpineBV_Miller

03/26/07 10:57 PM

#43615 RE: upndown1313 #43602

I'd call the secondary endpoints coincidental to the fact that a huge boost in HDL got essentially nothing in interarterial plague volume reduction and a negative effect on arterial thickness.

It's a class effect.