Fantastic paper! Seminole work. I have argued over the years that the DCVax-L work up to this point was not yet Nobel worthy, but assuming this research paper is validated and DCVax-L continues to develop as a major potential cancer treatment, the theoretical and practical implications together, from this paper, to me, seem potentially Nobel worthy, eventually. The Nobel committee is very slow in recognizing people and this will take a while to fully validate. Fantastic research!