flipper44,
One thing the bears have done well so far is to bury the idea of an immediate increase in value from Direct that the approval of L will bring. Those watching and analyzing will immediately realize that if NWBO could last 30 years to bring L forward as a fully personalized commercially available cancer vaccine then Direct will be the natural upgrade and vastly improved version of DC treatment. Once looked into carefully many of these same analysts will realize this upgrade happened as a result of learning during those years by a team focused on something others had ignored for so long that they actually fell prey to their own belief that personalized medicine could not possibly be scaled to a massively successful commercial enterprise. With NWBO being so tight lipped and having well protected IP, many analysts have had no way to accurately predict the what, when and how much value. By 2014 there were good clues that what NWBO had could be considered a threat to many big pharma companies and others invested in them. I believe some folks slowly began to realize how wrong they were about the threat and began to do all they could to defend against the advance of this platform technology. I believe that the 7 market makers likely represent just the tip of the spear of those realizing what is potentially at stake.
At first it likely seemed like a simple task to take down another underfunded development stage biotech due to all the potential setbacks, delays and pitfalls associated with this extremely complex work with only a small company and its investors to support it. What many still fail to realize is that Linda Powers had built a network of extremely dedicated and highly motivated researchers and problem solvers into her circle of influence and NWBO was really never doing this all by themselves. They were receiving cooperation in coordination with others who have been willing to play a part in the development of a bigger picture for the sake of the advancement to a cure for multiple types of cancer and other disease states. Roswell Park is just one example along with Shashi Murthy and Flaskworks as another. The board is becoming aware of the others Linda is connected too as well. One day so will the wider investment community. Best wishes.