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dewophile

10/25/25 9:39 AM

#256250 RE: mouton29 #256248

interesting, but certainly not all adjuvants are created equal. Shingrix has a very potent adjuvant (higher dose than in their RSV vaccine), and it would be interesting to see if there is a signal there. Same with Dynavax's hep B vaccine.
If someone ever wanted to study this prospectively you could use an empty LNP in an arm, but that is probably not practical and won't ever happen.
PS: my 85 yo mom always gets high dose flu which is not adjuvenated AFAIK