News Focus
News Focus
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poguemahone

10/02/25 8:33 AM

#501936 RE: PsuLion #501934

Losing credibility means they had it to lose.

I’m not sure they had it to lose.
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xodcode

10/02/25 8:41 AM

#501940 RE: PsuLion #501934

You are missing the important story if you are focused on A3-71 preliminary resulys!

The big news today is all about Blarcamesine:

https://www.anavex.com/post/anavex-life-sciences-announces-publication-of-oral-blarcamesine-describing-a-new-class-of-clinical-p?mc_cid=dd7566ccee


And yes, WGT!
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frrol

10/02/25 8:47 AM

#501941 RE: PsuLion #501934

Yes the PANSS, BACS, and CGI scores have been omitted. This is not something you want to see, and it means they are very likely not stat-sig. The safety and tolerability data is strong (re-affirming the years ago phase 1), and there are apparently "encouraging trends" with some biomarkers, though no data. Hopefully stat-sig, or close. We'll see eventually. Disappointing, but not surprising as an investor since the company had stopped mentioning the trial. This program may fade like Rett, at least for a while.

For a muscarinic modulator, though, tolerability is important. If we can find efficacy in some indication, 3-71 can be viable.

As for your friends' Cassava comparisons, that's over-reacting.
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Hoskuld

10/02/25 9:14 AM

#501948 RE: PsuLion #501934

LOL did all your MD friends text you this morning>? Too funny. Is that you Adrian or Jesse or Adam? Hilarious stuff.