Replies to post #779291 on NorthWest Biotherapeutics Inc (NWBO)

[sukus]

Agreed.

[skitahoe]

Chuigray,

While I agree that this is possible, I also believe it will take several years and like DCVax-L to be most effective, other therapeutics that work with it will have to be determined, or developed.

We need to realize that the DCVax's alone are beneficial, but they're far from curative in the majority of patients. Our vaccine is building a tremendous increase in T-cells and that's something that can be built upon.

I believe the DCVax's will be a part of the long term goal of curing cancer, but it won't do it all by themselves. It will take many year to go from using DCVax-Direct on inoperable cancers to pretreating cancers before surgery, and then perhaps eliminating the surgery completely. If I make the century mark, in 18 years, perhaps I'll see it.

Gary

[Doc logic]

Chiugray,

No chemo/rad needed although Direct may repotentiate salvage treatments of chemo/rad even if it does not deliver the cure in every case. DC treatments have been known to do this in the past. Improved Direct likely will not need much help to create complete responses and immune memory in most cases because enough significant targets will be hit in multiple metastases to create a complete collapse of cancer defenses in the tumor structures and targeting of shedding exozomes moving off site. Best wishes.