I may be wrong Gary but despite the fact that poly ICLC has not yet been submitted to a trial, I believe that physicians can routinely request its use for GBM patients because at this point there is enough evidence from small trials and RWE (including probably the UK compassionate program) that it greatly adds to the efficacy of DCVax-L. I will have to do some research as to the cost of adding polyICLC to the treatment but I believe the cost is low and the difference in efficacy substantial and I believe that it will be included from the get go to the reimbursement total. It would be a shame to not to include poly ICLC and wait for the results of a longwinded trial.