Replies to post #435955 on Amarin Corp Plc (AMRN)

[Whalatane]

I think you're making to much of this ...gross negligence etc .
Consider they had to raise significant funds to run R-IT .
Groks take on this

Practical and Statistical Considerations:
Adding a statin-intolerant arm would have increased the trial’s complexity, requiring a larger sample size to achieve sufficient statistical power for subgroup analyses.
The REDUCE-IT trial already enrolled 8,179 patients, and expanding it to include a distinct statin-intolerant cohort could have increased costs and logistical challenges.
Instead, the trial prioritized a well-defined population to maximize the clarity of the results.

Kiwi