Replies to post #489560 on Anavex Life Sciences Corp (AVXL)

[sab63090]

Thanks, even more powerful......

I hope to check in later in the day..............

I know Neal will be glad while I'm away! 😶

[georgejjl]

rx7171 and sab,

You said:

Clinicaltrials.gov notes trial participants as 71.

That. is correct BUT so is my post below.

The original information at Clinicaltrials.gov said that they estimated 40 total patients for both Part A and Part B and a previous press release stated that the Part A was completed with 16 participants therefore Part B originally would recruit 24 additional participants.

So Part B was increased from 24 to 55 participants a 129% increase.

Part A had 16 participants and Part B had 55 participants for a total of 71 participants.

My post below was and still is correct.

***************************************************************************

georgejjl
Re: None
Saturday, May 10, 2025 8:50:38 PM
Post# of 489579
Why do you think that Dr. Christopher Missling MS PhD MBA decided to increase the Phase 2 Part B schizophrenia trial from 24 patients to 55 participants that is a (31/24) 100%=129.2% increase? He said that he wanted to increase the power of the trial. The "power" of a trial, especially in a clinical trial, refers to its ability to detect a true difference between groups or interventions when one actually exists. It's essentially the probability of a true positive result.

Good luck and GOD bless,