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SkyLimit2022

03/11/25 5:02 PM

#753611 RE: manibiotech #753559

mani,



You’re actually highlighting the beauty of the Roswell deal—time

The most exciting aspect of acquiring the Roswell DC platform is that we are already years into its development and clinical investigation as a combo agent. When the NWBO press release was published, we were already in PII which took years to achieve!

When the news quoted and linked below was first published in 2020, the ongoing DC trials had not even started yet. Today, we know that the Phase I Roswell trials were successful and advanced to Phase II, with funding that includes peer-reviewed U.S. government grants.

The trials at Roswell resulted from peer-reviewed research that also took years …NWBO was quite fortunate to acquire the Roswell DC platform at Phase II, and those trials involve more than one distinct type of cancer too!


“Our approach overcame both primary, or initial, and acquired resistance, and we also saw evidence of tumor-specific systemic immunological memory, suggesting that this strategy may generate long-term anticancer responses even against hard-to-treat melanoma and breast tumors.”

https://www.broadcastmed.com/cancer/9753/news/new-roswell-park-strategy-for-overcoming-resistance-to-immunotherapy-unleashes-power-of-dendritic-cells

https://www.nature.com/articles/s41467-020-19192-z

Jump ahead a few YEARS from that 2020 headline and see where we are now with the Roswell DC platform …




https://clinicaltrials.gov/study/NCT04348747?a=15&b=29

https://clinicaltrials.gov/study/NCT04093323?a=39




https://www.prnewswire.com/news-releases/northwest-biotherapeutics-announces-exclusive-in-license-of-portfolio-of-dendritic-cell-technology-and-intellectual-property-302174237.html
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