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dewophile

01/27/25 9:06 AM

#254405 RE: WorstLuck #254403

what's weird is that there would typically have been a healthy volunteer study before this POC study, and for this disorder there is a good biomarker of activity - serum tryptase - so you would think you have a pretty good idea if the drug is active already in healthy volunteers
i don't follow the company so no idea if they announced healthy volunteer tryptase results but if that was omitted that would have been a serious red flag
if they had good suppression of tryptase in healthy volunteers then this result is really a surprise
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DewDiligence

04/02/25 11:51 AM

#254966 RE: WorstLuck #254403