Dont forget to include the margin delta's. Generic is happy with 20 to25% on average Amarin is currently 50 to 80% about 3-4 times Generics Amarin long term would like to be 70 to 80% but shorterm keeps cutting price in usa (which lowers margin) in order to maintain volume and market share. Cost advantage that Amarin has is most likely relatively small and not sufficient to offset generic business model for lower profits