Dr. Roger Stupp had his chance with input on the independent review of ECAs before the comparisons were made in unblinded form. He was paid by NWBO for some part in this process. No sense complaining after the fact that the ECAs helped demonstrate positive treatment effect. That seems like sour grapes or at best a tardy dismissal of method he agreed to be part of which does not shed a good light on him for being willing to play a paid part in its formation and utilization. Can’t have it both ways. His work and integrity is either good and valid or he can be bought. I think his work is good and valid. Maybe you don’t?; ). Best wishes.