Off-label drug use is common in cancer treatment because - many cancer drugs are effective against more than one type of cancer - cancer treatment often involves the use of combination chemotherapy ... The FDA usually does not approve combinations of chemotherapy. There are so many of them that it would not be practical to approve each combination.
Health insurance coverage of off-label drugs in cancer treatment Medicare and many insurance companies pay for off-label drugs for cancer treatment, as long as the off-label uses are listed in an approved compendium. A compendium is a collection of drug summaries put together by experts who have reviewed data about the drug’s use in patients.
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