I agree that JAMA was/is significant, and it is a landmark paper, but it has been ages since JAMA considering the lightning-fast evolution of immunotherapy—a lot has developed since JAMA!
Today, we have combos to consider and combos are a whole new ballgame! Our fuddy buddies are really going to have to step up their game as combo data emerge from UCLA and Roswell while additional combo studies soon commence!