100%.
Imagine a CEO who takes 20 years to develop a single treatment in a single cancer knowing the likelihood of some other effective treatment taking the lead, and she has no backup plan for shareholders...Well, at least she had one or two for herself.
Now, as fate would have it, GBM still has no good treatments, but LP could not have known that. And, in just the last few years, as management was trying to get from data lock to submission, a whole new crop of intriguing therapies has arrived to compete.