You are right that some of these small bios are taxing our patience or at least make it frustrating to hold. I have invested in a group of them for the potential they hold and will look at them as a group insofar as what return I will be getting on the investment.
ALLO, ARDX, EYEN, TLPH, RZLT, UNCY. I do have other small bios but I consider them separate since they have approved products already selling in the marketplace. AXSM, CRSP, AUPH, BCRX, CRMD.