The potential of DC VAX is to cannibalize 25 to 50% of all chemotherapy drugs within a five year period post approval
As of today DCVax is trying to get approved as an addition to chemo in a smallish market in an orphan designation (orphan means a small number of patients),
A long might hope with FDA and EMA it replaces a bit of chemo in rGBM. That would be well under 1% of all chemo.