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Hosai

07/28/24 7:07 PM

#465224 RE: Doc328 #465220

Dropout was a little higher than expected by 48 weeks but was higher in the placebo group than in the 30mg group as a %.
Either way what is clear is the drug beat placebo in ADAS - COG and CDR SB with p values under 0.025, in brain volume reduction loss and in regards to plasma 42/40 and PTAU.
Worth reminding that this was with only around 10% screening in the original enrollment, unlike Donnenamab and Lecanumab who screened out 70-80%.