I must say Doc logic that I am somewhat confused about your opinion that the SP is going to be crushed up to or even after MHRA approval? I also do expect the SP to be increasingly suppressed up to approval and perhaps somewhat beyond approval but I doubt that this can last for more than several months. What interests me to know is your projected time as to how long the shorts and manipulators are likely to have the upper hand and the reasons for your estimates.
Even without intervening post-approval positive events such as a partnership or a MTD denial, the UK approval itself may have a very positive effect and that may start several months after approval simply because of the increasing profits obtained from insured UK patients. The question then is for how long can the shorts and manipulators retain their effectiveness in suppressing the SP.