Replies to post #418555 on Amarin Corp Plc (AMRN)

[johnhancoque]

But, it's off patent zip. And besides, as Alex duper pisses away the patent life, almost a year now on some ridiculous go it alone approach. Patents will be a thing of the past by the time that would benefit anyone and vascepa will be nearly everywhere and almost free it will be so cheap. Tats is absolutely right, vascepa is doomed and especially under time waster Alex duper belt

[rosemountbomber]

I guess the side effects were enough to get Pfizer to put a halt on their version of a similar drug. Of course I have read articles saying that semaglutide is flying off yhe shelves and drug stores are having a hard time staying stocked.

[JRoon71]

Zip, I don't think Tats is entirely wrong about GLP-1 drugs. However...If Vascepa DOES prove to have legit efficacy against AD (even if it's not considered as "effective" as GLP-1 drugs), if Amarin (or BP) does a good enough job of PR/marketing its effectiveness, people and docs will be ALL OVER it because if its safety profile (and cost vs. GLP-1's). AND...rather than NEGATIVE side-effects, you are talking about POSITIVE side-effects from taking Vascepa. Shit, it's just a more efficient delivery system for EPA. So if docs and pts could all understand the net positive outcomes of taking Vascepa, it could be HUGE.

[Tatsumaki]

Cost and Side effects always matter a great deal....

Meanwhile, GLP-1s are selling $10s of billions annually. Headed to $100B despite your claim that "cost and side effects" are a major concern. The market has proven the cost and side effects are worth the benefits of the drugs. Even before AD is considered. That mindset isn't going to change suddenly if/when AD gets approval. Only thing that'll change it now is having people die on the drug.

Diabetes and overweight are a nuisance...Alzheimers is a curse.

All 3 are related metabolic diseases for most individuals. CVD as well. GPL-1s work on all of them because it significantly reduces caloric intake allowing the metabolism to function normally and not get overwhelmed. Take away the excessive caloric/carbohydrate intake, those metabolic disorders improve. It's much closer to addressing the actual root cause of those diseases than V is.