Replies to post #437884 on Anavex Life Sciences Corp (AVXL)

[kevindenver]

Imagine the marvel once full data is finally released. I will be curious to see which groups respond better.

Alzheimer's isn't my personal fear, nor should it be if we believe our 23andMe test. But, I am terrified of the dementias related to alpha synuclein.

[georgejjl]

Investor2014: You are WRONG!!!

The following is from the results of the Phase 2a trial with Blarcamesine for the treatment of Alzheimer’s disease.

75% of APOE e4 carriers in the high Anavex 2-73 concentration cohort

Notice the significant covariates identified in he MMRM-LME model are:

SIGMAR1 (p<0.0080)

COMT (p<0.0014) and

APOE e4 (p<0.0001)

See slide #15 and #16

http://www.arianapharma.com/wp-content/uploads/2019/03/ANAVEX2-73_CTAD_2018_Presentation_v2.pdf

GOD bless,