whereas "we don't got this" is a conclusion that follows from assumptions that are simply not supportable.
Totally incorrect definition of a NOT WGT premise. Skepticism is NOT blatant rejection. It is however more measured and conservative. Demanding that if not in agreement you are wrong is a fallacy of many debater's assertion(s).
Quote: "I most want to know when Fragile X and PD and other pivotal trials will commence."
I would think that pivotal trials on Fragile X, etc will start after they announce a successful P 2/3 trial with Excellence Rett. Once that is achieved, they can submit the NDA and get approval.
Once approved, they can repurpose A2-73 and run a simple P3 trial for efficacy on each disease.