All written out of deep ignorance, bias and chauvinism of one sort or another. These people have no experience with DCVax-L. The fact is, the company has lots of additional data to disprove these ridiculous commentaries and opinion pieces as well, and their critiques are based frequently on erroneous other commentaries, not even on the basics in the JAMA piece that they could have learned, if they had read more carefully, and that speaks volumes about the carefulness of their critiques. Further, these critiques are not studies disproving anything, and therefore they have no scientific weight. In addition, you have that U Penn study using the different scanning technique, and that validates the results. Moreover, you have numerous papers and studies, many more than these commentaries, that speak very highly of these results and reference them in survey articles. Numerous articles, many more than these critiques. Virtually ALL of the researchers writing these critiques are TTF focused in their research, and TTF didn't even have a valid placebo arm in any context. Some are hoping other areas that they are focused on bear fruit. As for TTF, it is a device, and therefore had to meet only the lowest of scientific standards for approval. They dressed up their studies nicely and tried to make the studies they did look like they were as scientific as drug trials, but the Washington State critique tore the core study apart, and the UK's NICE did not approve it for patients generally. The reality was, they pretended and implied things, rather than being frank about what their study represented. And the idea is to pass it off as a truly scientific thing that could cure brain tumors when that seems honestly, quite absurd. They attack other better done studies AS IF by doing so, they can elevate their own work. However, if TTF slows things down or if it has even just a placebo effect and makes people feel like it is having an effect, I'm not against it. But TTF / Optune at $21,000 a month!? There are way better ways to spend the money to care for these patients and to do the research and DCVax-L is clearly the better way to go, as we can see from the indications in the adjuvant and combination trial. The days of these kinds of ignorant critiques are numbered. So you should enjoy pretending that these guys are saying something useful or ethical. The days when they can write such garbage and get respect are numbered.
They want so badly to be the standard of care before something like DCVax-L comes along and completely displaces them. Of course they would write this garbage.
Also, I don't think these doctors think they can keep DCVax-L from being approved. They wrote those critiques so that they can keep prescribing that TTF garbage and make their false argument that their study was better, which is nonsense.
Bullish
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