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Investor2014

06/06/23 1:47 PM

#417873 RE: Steady_T #417872

Exactly no mention of whether that’s using AUC or baseline to EOS.
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georgejjl

06/06/23 1:57 PM

#417876 RE: Steady_T #417872

linear mixed-effects models for repeated measures (MMRM)

https://thestatsgeek.com/2020/12/30/mixed-model-repeated-measures-mmrm-in-stata-sas-and-r/#:~:text=Linear%20mixed%20models%20are%20a,and%2For%20correlated%20residual%20errors.

Linear mixed models are a popular modelling approach for longitudinal or repeated measures data. They extend standard linear regression models through the introduction of random effects and/or correlated residual errors. In the context of randomised trials which repeatedly measure patients over time, linear mixed models are a popular approach of analysis, not least because they handle missing data in the outcome ‘automatically’, under the missing at random assumption. Because of this a mixed model analysis has in many cases become the default method of analysis in clinical trials with a repeatedly measured outcome.



Good luck and GOD bless,