Dr. Missling has zero control over whether Blarcamesine works. His compensation should be for things that are within his control, such as getting a trial initiated and advancing the ball closer to the end zone. Later on, his compensation should be tied to things like sales, net profits, and market cap. Besides, if the trial(s) fail those warrants become worthless regardless of when they were granted or exercised.
It's sort of the same reason why doctors aren't paid when a patient is fully healed, or why pilots aren't paid after each successful landing.