Replies to post #547766 on NorthWest Biotherapeutics Inc (NWBO)

[hoffmann6383]

First successful nGBM and rGBM trial in nearly 3 decades. Unseen long tail survival data. This does not come cheap or quick. While some want to highlight the inefficiencies of our drug development system, that is in the past. Write your congressman/woman if you want to become a champion to fix the system.

The trial is over and the data is great. Lets move on to relevant topics.

As far as the comment:

Man what a trainwreck from a trial design and management standpoint.

Appreciate your opinion but experts, the MHRA and the FDA disagree with your assertion.

Have a great one Gro!

[drugrunner]

Everyday you gripe about a 16 yr trial..

Get some new material

Maybe turn the page in the handbook

I am positive there is another nonsensical argument you could attempt to make

[Dr Bala]

The data is great. Thanks, HyGro.

[SkyLimit2022]

The P3 study was led by clinical trial experts, and the trial design and its data were independently validated.

https://expertscape.com/au/glioblastoma/Liau%2C+L




https://doi.org/10.3171/2020.12.FOCUS20954

https://www.kcl.ac.uk/people/keyoumars-ashkan

https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847

[dstock07734]

HyGro,

I just have several questions and I would appreciate your honest answers.

1. Can you explain why over 90% percent patients were recruited in the last five years of the trial?

2. If everything is as bad as you depict, why did BMY come for collaboration with NWBO? BMY seems like holding no grievance after the collaboration deal was withdrawn last and plans to collaborate on another combo trial.

3. You do know the expanded access program for dcvax which started about the time when the trial was finished. How could FDA approve such program if DcVax had a bad record and after the partial hold?

https://clinicaltrials.gov/ct2/show/NCT02146066?cond=Expand+%2B+dcvax&draw=2&rank=1

4. The data from Linda Liau's latest present which has close 60% patients living over 800 days is based on dcvax. You would agree, right?

5. Do you agree that there were patients who dropped out the trial because the pseudoprogression was unknown back then and was considered as true progression?

[jfr1611]

Orange is your new colour. Soon.

[Roman516]

Once again, this is your personal opinion.

[AceT]

I think it is time to start getting concerned about the trail of breadcrumbs that will lead to paid intentionally misleading postings.....