Replies to post #546837 on NorthWest Biotherapeutics Inc (NWBO)

[TopherTink]

do you even know that the dosing with DCVAX happens multiple times after the first dose? patients keep getting it for years.

[SkyLimit2022]

The P3 study was led by clinical trial experts, and the trial design and its data were independently validated.











https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847

[Reefrad]

But dcvax doesn’t work so even if this were true why would it matter?

[Red_Right_Hand]

Actually, it's more like 100%, since the trial protocol provides for at least 5 doses and aims for up to 10 doses:

8.7 ADMINISTRATION OF DCVAX-L OR PLACEBO
Over the course of the study patients will receive up to 10 DCVax-L or placebo
injections at days 0, 10, 20, and at months 2, 4, 8, 12, 18, 24 and 30.

http://jamanetwork.com/article.aspx?doi=10.1001/jamaoncol.2022.5370

[DL7]

My mother was in the trial. She was not double dosed and there was no way to get a double dose. When her GBM came back she had a second resection. I spoke to her neuroncologist and I spoke to NWBO. It was not possible. Those that were in the placebo received DC Vax after progression and it was made from the original tumor and frozen