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dewophile

11/04/22 9:51 AM

#244411 RE: DewDiligence #244410

what do you think of the data?

my quick take

cohorts I and K got 90 Q8 weeks, and cohort E 60 Q4 weeks

2 patients in K and one in E achieved undetectable HBSAg. It looks like one of the 2 in cohort K started to rebound 28 weeks after stopping tx but hard to tell. If you include this pt then that makes 3 out of 20 at the highest doses (none at lower doses) may have functional cures.

adding their core inhibitor didn't boost responses at all