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Re: DewDiligence post# 244410

Friday, 11/04/2022 9:51:05 AM

Friday, November 04, 2022 9:51:05 AM

Post# of 257484
what do you think of the data?

my quick take

cohorts I and K got 90 Q8 weeks, and cohort E 60 Q4 weeks

2 patients in K and one in E achieved undetectable HBSAg. It looks like one of the 2 in cohort K started to rebound 28 weeks after stopping tx but hard to tell. If you include this pt then that makes 3 out of 20 at the highest doses (none at lower doses) may have functional cures.

adding their core inhibitor didn't boost responses at all

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