You’re right georgejjl, Thank you. 23% is about 72 responders so spitballing might be about right.
And 12% of 340 is 40 SuperHiemers.
Don't expect any super responders from the placebo cohort, which is approximately 169 from the 509 participants.
So, 60 super responders from the 340 participants taking Blarcamesine each and every day would be 60/340=17.6%, which is lower than I expect. I expect approximately 23% super responders from the Phase 2b/3 trial.
I expect all 180 high dosage to be super responders as DrM said high dosage is the common denominator.. didn’t say common denominator of what. But what else could it be other than success..
Than I expect 1/2 of all 30 Mg to be at baseline or higher because this is Early Alzheimers sufferers and their S1 r signaling should be strong enough to catch on at 30 Mg..
So about 270 of the 340 dosed should be tremendous responders and all of the dosed patients should be better than average of placebo..
Maybe I said something about the horrific recent fda decisions regarding children and ineffective , evemn dangerous medicines..sometimes those notes just sneak in my posts trying to save children