Replies to post #521860 on NorthWest Biotherapeutics Inc (NWBO)

[dr_lowenstein]

Wow next we will hear it cures hangnails and us the fountain of youth lol

[biosectinvestor]

I think the fact that it works against Glioblastoma, and given the brain barrier, plus lots of real world data of other patients getting it, it will lead to off-label prescription and then more data that I believe should get it more rapidly ultimately to other oncology patients. The 21st Century Cures Act was all about getting these treatments to more patients more rapidly. That is a core purpose of that law, duly enacted and signed into law.

Combination trials should also both accelerate it and, I believe, increase indicia of efficacy. Then you’ve got the still in trial expanded adjuvant trial which uses Poly ICLC. Should those results pan out, that’s a giant game changer in oncology. Period. Assuming then the further combination of the two in the combination trial with Keytruda, also currently playing out, we could see something major ahead. It’s an extremely exciting time.

So I agree.

[Maverick0408]

Sorry to break your bubble but doesn’t work that way in real life! Without more data in other types of cancer, the medical doctors are not going to suggest this route to their patients. It would be premature. Plus 99% of the doctors outside neuro world has no idea what DCVAX is. And without reimbursements, it’s even more of a hard sell. We have all seen how compassionate use has gone so far.

It will be a multi year process and quite a bit of data accumulation in specific indications before the medical community gets behind even for off label use, unfortunately! Further, RA and reimbursements are a different ball game altogether.