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SkyLimit2022

09/05/22 7:13 PM

#511292 RE: HyGro #511284

https://clinicaltrials.gov/ct2/show/NCT04201873

Both groups are receiving DCVax-L

Group A (pembrolizumab, ATL-DC, poly ICLC)
Beginning 14 days prior to scheduled surgery, patients receive pembrolizumab IV over 30 minutes. After surgery, patients receive pembrolizumab IV over 30 minutes on day 1. Cycle repeats every 3 weeks in the absence of disease progression or unacceptable toxicity. Patients also receive ATL-DC ID with poly ICLC IM every 2 weeks for up to 3 doses in the absence of disease progression or unacceptable toxicity.

Group B (placebo, ATL-DC, poly ICLC)
Beginning 14 days prior to scheduled surgery, patients receive placebo IV. After surgery, patients receive placebo IV on day 1. Cycle repeats every 3 weeks in the absence of disease progression or unacceptable toxicity. Patients also receive ATL-DC ID with poly ICLC IM every 2 weeks for up to 3 doses in the absence of disease progression or unacceptable toxicity.

virtualtrials.org/dcvax.cfm

https://clinicaltrials.gov/ct2/show/NCT04201873
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Roman516

09/05/22 10:43 PM

#511344 RE: HyGro #511284

We know that there are many doctors who want to see DCVax
commercially approved as it should be. Just a matter of time, weeks, few months, IMPO.