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HyGro

08/29/22 11:11 PM

#509245 RE: Dr Bala #509224

But yet OS data was confounded during the trial. But evidently some investors may not have read NWBO's SEC 10K:
"Under the Protocol the primary endpoint was progression free survival, or PFS, and the secondary endpoint was overall survival, or OS. Both of these endpoints were confounded: the PFS endpoint by pseudo-progression, and the OS endpoint by the “crossover” provision in the trial design, which allowed all of the patients in the trial to cross over to DCVax-L treatment after tumor recurrence (while remaining blinded as to which treatment they received before tumor recurrence)."