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FeMike

06/01/22 8:21 AM

#480432 RE: flipper44 #480429

The KM curve really doesn't do justice to the magnitude of this result. It is wildly impressive.
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erik007tc

06/01/22 8:22 AM

#480433 RE: flipper44 #480429

Dcvax-L is the new sheriff in town, Chemo is dead.
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exwannabe

06/01/22 12:03 PM

#480530 RE: flipper44 #480429

Looking at that slide deck again, it really is amazing to me that over 10% of patients with incomplete surgeries that left significant residual tumor, when treated initially with DCVax-l, lived over five years.


The DCVax-L trial was the only one with "intent for near complete resection". Others allowed partials and even biopises.

Wonder if those with more than 1 cm^2 left (the cut line for MRD) in the DCVax-L trial that do have SRD are likely much more like the MRD population?

This is in addition to the fact that the 3 main variables, age/meth/extent all favored DCVax-L and the results presented did not adjust for that. Oh, they do have adjusted numbers, but did not want to show them.