Replies to post #374825 on Amarin Corp Plc (AMRN)

[Whalatane]

O U raised an interesting question .
The CAC measures coronary calcium correct ? ...not soft coronary plaques that haven't calcified ?
Most heart attacks are caused by soft plaques erupting and the contents blocking blood flow . Calcified plaques ( which happens more as we age ) lead to narrowing of coronary arteries which in turn restrict blood flow .
Correct if wrong .
Agree that all diabetics should be on V especially if theres a family history of CV events .
Why is your LDL still above 100 mg/dl ...when U obviously have a family history of events ?
Kiwi

[Whalatane]

O. I took the time to read some of your other posts .
With your family history I wouldn't rely on a CAC score to think U are home free .
CAC measures the hard /calcified plaques ...not the soft plaques which are typically more dangerous

What's really dangerous is the soft plaque, and experts estimate that there is approximately four times as much soft plaque present as hard, or calcified, plaque. When soft plaque ruptures, it's similar to having a pimple inside the artery that breaks open.

Vascepa as per the EVAPORATE trial makes these soft plaques less vulnerable to rupturing ...but I suggest you drive down your LDL cholesterol numbers closer to 50 mg/dl if possible ( stronger statin dose with Zetia and even maybe a PCSK9 )
Kiwi