The next one would be a lot faster I think. I think similar to the solid tumor trial they did on DCVax-Direct trial phase 2. Imo.
The Direct P1/2 was first posted in summer 2013. The P2 phase was supposed to start around end of 2014 or so. 8 years later it has not even opened for enrollment. And that would still have not been pivotal.
Direct has now been on the shelf for over 7 years gathering dust.