Diver, please correct me if I'm wrong, but I believe the FlaskWork device takes roughly the same amount of time for each batch of the vaccine. The big difference is ten or more machines can probably be put in the space of a single clean room needed to produce a single batch at a time.
I'd also like to bring up CRL. We all seem to deal with the capability being developed at Sawston, but I've heard no ones estimate of how many batches of the vaccine CRL is capable of making simultaneously. As I understand it, without the FlaskWork device an individual clean room is needed for slightly over a week for each batch. I believe that CRL has lots of clean rooms, the question is, how many will they devote to the production of DCVax-L. I believe their capacity will greatly exceed that of Sawston when all of it has been built out.
I'd also like to know people's thoughts on the Journal having difficulty getting documentation needed to do the peer review. Perhaps I'm wrong, but it would seem to me that everything they need should be found in all the information the company is working with in creating the BLA. If this isn't the case, why can't the company duplicate it and provide it to the peer reviewers.
Gary
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